clustering and linking metabotropic glutamate receptors group I with the inositol triphosphate receptors regulator of GRMs signaling
may play a role in regulation of protein degradation by ubiquitin-proteasome systems and this function may be specific to HOMER2 proteins among HOMER family proteins
may be involved in cell growth
cooperates with MYO18B for the suppression of anchorage-independent growth
being a negative regulator of T cell activation
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
cellular trafficking transport
PATHWAY
metabolism
signaling
neurotransmission
a component
INTERACTION
DNA
RNA
small molecule
protein
interacts with the PPXXF motif in GRM1, GRM5, RYR1, RYR2, ITPR1, SHANK 1 and SHANK3
interacting with MYO18B (partly co-localize on F-actin)
interacting with UBXN1 (specifically interacted and colocalized with HOMER2 proteins, and this specific interaction may play a role in regulation of protein degradation by ubiquitin-proteasome systems, function that may be specific to HOMER2 among HOMER family proteins))