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FLASH GENE
Symbol PKIA contributors: - updated : 29-07-2004
HGNC name protein kinase (cAMP-dependent, catalytic) inhibitor alpha
HGNC id 9017
Location 8q21.11-q21..133      Physical location : 79.428.335 - 79.515.484
Synonym symbol(s) PRKACN1
DNA
TYPE functioning gene
STRUCTURE 87.00 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Map cen - D8S526 - IL7 ,PKIA - D8S1736 - D8S275 - qter
Authors GeneMap
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 2184 - 76 heart Zheng,Olsen
- splicing 2055 - 76 skeletal muscle Zheng,Olsen
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Lymphoid/Immunespleen    
Nervousbrain    
Reproductivemale systemtestis   
Urinarybladder    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY cAMP-dependent protein kinase (PKA) inhibitor family
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • protein kinase (CAMP-dependent,catalytic) inhibitor alpha, may be involved in negative regulation of protein kinase activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS