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FLASH GENE

Symbol

ANXA8

contributors: mct - updated : 30-03-2016

HGNC name	annexin A8
HGNC id	546

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in gastric cancer tumoral     --other   ectopically expressed in pancreatic cancers

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	both KRT19 and ANXA8 mRNA may be useful markers for detecting lymph node metastases in OSCC (oral squamous cell carcinoma) patients
Therapy target

ANIMAL & CELL MODELS

Anxa8 expression in the mouse mammary gland was strong during pre-puberty before the expansion of the rudimentary ductal network and was limited to a distinct subpopulation of ductal luminal epithelial cells