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FLASH GENE
Symbol ACAD8 contributors: - updated : 09-03-2007
HGNC name acyl-Coenzyme A dehydrogenase family, member 8
HGNC id 87
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer tetramer
HOMOLOGY
interspecies ortholog to murine Acad8
Homologene
FAMILY acyl-CoA dehydrogenase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION extracellular
    intracellular
intracellular,cytoplasm,organelle,mitochondria
intracellular,cytoplasm,organelle,membrane
basic FUNCTION
  • playing a role in transcriptional coactivation within the ARC complex
  • isobutyryl-CoA dehydrogenase that functions in valine catabolism
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism aminoacid , energetic
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
  • FAD
  • ETF electron acceptor
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) ACAD8D
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS