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FLASH GENE

Symbol

CBFB

contributors: mct - updated : 08-02-2018

HGNC name	core-binding factor, beta subunit
HGNC id	1539

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

AMLM4EO

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral       protein chimeric chimeric fusion protein with MYH11 in acute myeloid leukemia with good prognosis constitutional     --over   in DMD with milder phenotype tumoral   inversion     in acute myeloid leukemia (AML-M4Eo) with inversion inv(16)(p13;q22) or t(16;16)(p13;q22)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS