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FLASH GENE

Symbol

ALOX15

contributors: mct/npt - updated : 07-02-2023

HGNC name	arachidonate 15-lipoxygenase
HGNC id	433

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Cardiac fibrosis increased in Alox15 transgenic mice with advancing age and was associated with the infiltration of macrophages
	Mice lacking Alox15 in &
	946; cells exhibit an increase in a population of beta cells expressing the gene encoding the protein programmed death ligand 1 (PD-L1), which engages receptors on immune cells to sssuppress autoimmunity