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FLASH GENE
Symbol CLDN15 contributors: npt/ - updated : 08-03-2007
HGNC name claudin 15
HGNC id 2036
Location 7q22      Physical location : 100.875.373 - 100.882.101
Synonym name clostridium perfringens enterotoxin receptor
Synonym symbol(s) FLJ42715, MGC19536
DNA
TYPE functioning gene
STRUCTURE 5.74 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 1258 24.2 228 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
Digestiveintestinelarge intestinecolon  
Reproductivefemale systembreast   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal, pregnancy
Text liver
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • four putative transmembrane segments
  • HOMOLOGY
    Homologene
    FAMILY
  • claudin family
  • CATEGORY adhesion , structural protein
    SUBCELLULAR LOCALIZATION     plasma membrane,junction,tight
    text integral membrane protein
    basic FUNCTION
  • tight junction specific obliteration of the intercellular space
  • creating charge specific channels in the paracellular space
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • major structural components of tight junction (TJ) strands
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS