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FLASH GENE

Symbol

CLDN9

contributors: mct/npt - updated : 11-04-2023

HGNC name	claudin 9
HGNC id	2051

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

DFNB116

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --other   aberrant CLDN9 expression is a predictor of poor prognosis for endometrial cancer

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	could potentially be used as a diagnostic and/or prognostic marker for subtypes of pituitary adenomas (
	CLDN9 may be an important biomarker for invasive pituitary oncocytomas
Therapy target
	System Type Disorder Pubmed tumor     could potentially be used as an immunotherapy target for subtypes of pituitary adenomas

ANIMAL & CELL MODELS

ENU–induced mouse mutant (nmf329) with Claudin 9 mutation exhibits recessively inherited deafness (Nakano 2009)