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FLASH GENE

Symbol

CPNE7

contributors: - updated : 22-12-2004

HGNC name	copine VII
HGNC id	2320

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - - 2470 59.6 - - - variant 2 - - 2657 70.3 633 - -

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	two Ca(2+)- and phospholipid-binding domains known as 'C2 domains'
	and a C terminal region distantly related to the A domain

HOMOLOGY

Homologene

FAMILY

copine family

CATEGORY

transport

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytosolic,vesicle
text	secretory vesicle

basic FUNCTION

calcium-dependent,phospholipid binding protein,potentially involved in regulating membrane trafficking and in protein-protein interactions

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

cellular trafficking transport

text	vesicular transport
	membrane trafficking

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule
	phospholipid binding

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS