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FLASH GENE

Symbol

SPRR1A

contributors: mct - updated : 16-05-2023

HGNC name	small proline-rich protein 1A
HGNC id	11259

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   significantly increased in atopic dermatitis (AD) skin tumoral     --over   significantly increased in colorectal cancer tissues compared with those in adjacent non-cancerous tissues, and associated with a significantly worse event- and relapse-free survival time tumoral     --over   associated with a poor prognosis in pancreatic ductal adenocarcinoma (PDAC)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	may serve as a potential biomarker for the prognosis of colon cancer
	may serve as a novel prognostic marker in pancreatic ductal adenocarcinoma (PDAC)
Therapy target

ANIMAL & CELL MODELS