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FLASH GENE

Symbol

SIK3

contributors: mct - updated : 14-06-2016

HGNC name	SIK family kinase 3
HGNC id	29165

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

	biliary disorders in Sik3(-/-) mice are associated with the dysregulation of gene expression programs that respond to nutritional stresses and are probably regulated by nuclear receptors
	Sik3-deficient mice showed dwarfism as they aged, whereas body size was unaffected during embryogenesis