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FLASH GENE
Symbol ATP11B contributors: mct/npt - updated : 02-02-2013
HGNC name ATPase, class VI, type 11B
HGNC id 13553
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunelymph node   highly
 thymus   highly
Nervousbrain    
Reproductivemale systemtestis   
Urinarybladder   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a KVIRLIKIS sequence in the catalytic loop of ATP11B
    • HOMOLOGY
    interspecies homolog to mus chromaffin granule ATPase II
    Homologene
    FAMILY
  • cation transport ATPase (P-type) family
  • type IV subfamily
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,organelle,endosome
    intracellular,nuclear envelope,int
    text integral membrane protein
    basic FUNCTION RING finger-binding protein that targets transcription factors to specific domains within the nucleus
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • TMEM30 is not essential for the ER exit or TGN localization of ATP9B, whereas TMEMA, but not TMEM30B, is required for ER exit and/or recycling endosomal localization of ATP11B
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS