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FLASH GENE

Symbol

ATP11B

contributors: mct/npt - updated : 02-02-2013

HGNC name	ATPase, class VI, type 11B
HGNC id	13553

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_014616 30 - 7347 NP_055431 134 1177 - 2001 11058586

EXPRESSION

Type

widely

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Lymphoid/Immune lymph node       highly   thymus       highly Nervous brain         Reproductive male system testis       Urinary bladder       highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a KVIRLIKIS sequence in the catalytic loop of ATP11B

HOMOLOGY

interspecies

homolog to mus chromaffin granule ATPase II

Homologene

FAMILY	cation transport ATPase (P-type) family
	type IV subfamily

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,membrane
	intracellular,cytoplasm,organelle,endoplasmic reticulum
	intracellular,cytoplasm,organelle,endosome
	intracellular,nuclear envelope,int
text	integral membrane protein

basic FUNCTION

RING finger-binding protein that targets transcription factors to specific domains within the nucleus

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

TMEM30 is not essential for the ER exit or TGN localization of ATP9B, whereas TMEMA, but not TMEM30B, is required for ER exit and/or recycling endosomal localization of ATP11B

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS