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FLASH GENE
Symbol ATP11B contributors: mct/npt - updated : 02-02-2013
HGNC name ATPase, class VI, type 11B
HGNC id 13553
Location 3q27.1      Physical location : 182.511.290 - 182.639.419
Synonym name
  • related to mus chromaffin granule ATPase II homolog
  • probable phospholipid-transporting ATPase IF
    • Synonym symbol(s) KIAA0956, ATPIF, ATPIR, DKFZP434J238, DKFZP434N1615, MGC46576
    EC.number 3.6.3.1
    DNA
    TYPE like-sequence
    STRUCTURE 128.13 kb     30 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    30 - 7347 134 1177 - 2001 11058586
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunelymph node   highly
     thymus   highly
    Nervousbrain    
    Reproductivemale systemtestis   
    Urinarybladder   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a KVIRLIKIS sequence in the catalytic loop of ATP11B
    • HOMOLOGY
    interspecies homolog to mus chromaffin granule ATPase II
    Homologene
    FAMILY
  • cation transport ATPase (P-type) family
  • type IV subfamily
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,organelle,endosome
    intracellular,nuclear envelope,int
    text integral membrane protein
    basic FUNCTION RING finger-binding protein that targets transcription factors to specific domains within the nucleus
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • TMEM30 is not essential for the ER exit or TGN localization of ATP9B, whereas TMEMA, but not TMEM30B, is required for ER exit and/or recycling endosomal localization of ATP11B
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS