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FLASH GENE
Symbol CBX6 contributors: npt/mct - updated : 14/10/2008
HGNC name chromobox homolog 6
HGNC id 1556
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivesalivary gland   highly
Lymphoid/Immunespleen   highly
Nervousnerve   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a chromatin organization modifier (chromo) domain conserved and chromobox regions were dispensable for chromatin association
    • HOMOLOGY
    interspecies homolog to Drosophila polycomb-like (PcG) chromobox 6
    homolog to murine Numbl
    Homologene
    FAMILY Polycomb group proteins family
    CATEGORY DNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • involved in the compaction of chromatin
  • transcriptional repressor recruited to many developmental control genes
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS