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FLASH GENE
Symbol ZNF197 contributors: - updated : 04-09-2006
HGNC name zinc finger protein 197
HGNC id 12988
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal KRAB (Kruppel-associated box) domain
  • a SCAN box, leucine-rich, mediating self-association and oligomerization
  • 22 tandemly arrayed C2H2-type zinc fingers
    • conjugated MetalloP
    HOMOLOGY
    interspecies homolog to Drosophila CG6654
    homolog to C.elegans B0524.1
    Homologene
    FAMILY krueppel C2H2-type zinc-finger protein family
    CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION may be involved in transcriptional regulation
    CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    zinc Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in some thyroid papillary carcinomas
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS