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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

GALNT6

contributors: mct - updated : 10-06-2011

HGNC name	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
HGNC id	4128

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   has transformational potentials through disruptive acinar morphogenesis and cellular changes similar to epithelial-to-mesenchymal transition in normal mammary epithelial cell, MCF10A ( tumoral     --over   might contribute to mammary carcinogenesis through aberrant glycosylation and stabilization of MUC1

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer reproductive breast screening of GALNT6 inhibitors would be valuable for the development of novel therapeutic modalities against breast cancer

ANIMAL & CELL MODELS