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FLASH GENE
Symbol CA5B contributors: mct - updated : 29-03-2014
HGNC name carbonic anhydrase VB, mitochondrial
HGNC id 1378
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal mitochondrial signal sequence
    • conjugated MetalloP
    isoforms Precursor
    HOMOLOGY
    Homologene
    FAMILY eukaryotic-type carbonic anhydrase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    basic FUNCTION
  • carbonic anhydrase VB
  • reversibly hydrating Co2 in cellular ion transport and pH homeostasis
  • CA5A, CA5B are pivotal in providing HCO3&
    • 8722; for multiple mitochondrial enzymes that catalyze the formation of essential metabolites of intermediary metabolism in the urea and Krebs cycles
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS