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FLASH GENE
Symbol ACAA2 contributors: mct - updated : 30-08-2008
HGNC name acetyl-Coenzyme A acyltransferase 2
HGNC id 83
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a non-cleavable amino-terminal targeting signal
    • HOMOLOGY
    Homologene
    FAMILY
  • thiolase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    basic FUNCTION
  • acetyl-CoA acyltransferase 2, mitochondrial-3-oxoacyl-coenzyme A, thiolase, concluding the step of fatty acid beta oxidation
  • catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein functional BNIP3 binding partner (possible linkage between fatty acid metabolism and apoptosis of cells)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS