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FLASH GENE
Symbol FAU contributors: mct - updated : 09-04-2020
HGNC name Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30
HGNC id 3597
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --other  
dysregulated expression of FAU and MELK is associated with poor prognosis in breast cancer
tumoral     --low  
in human breast, prostate and ovarian tumours
Susceptibility to Recurrent pregnancy loss (RPL)
Variant & Polymorphism SNP
  • FAU rs769440&
  • 8201;G allele had higher frequencies in patients with RP
    Candidate gene
    Marker
  • attractive target for improvements in breast cancer risk prediction and prognosis
  • Therapy target
    SystemTypeDisorderPubmed
    respiratoryCF (mucoviscidosis) 
    may offer a therapeutically relevant panel of drug targets to correct basic defects in F508del-CFTR processing
    cancerreproductivebreast
    attractive target for improvements in breast cancer therapy
    ANIMAL & CELL MODELS