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FLASH GENE

Symbol

GADD45B

contributors: shn/mct - updated : 04-01-2015

HGNC name	growth arrest and DNA-damage-inducible, beta
HGNC id	4096

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Mice with Gadd45b deletion exhibit specific deficits in neural activity–induced proliferation of neural progenitors and dendritic growth of newborn neurons in the adult hippocampus (Ma et al 2009)
	hypertrophic zone of the Gadd45beta(-/-)mouse embryonic growth plate is compressed, and expression of type X collagen (Col10a1) genes is decreased