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FLASH GENE
Symbol SDS contributors: mlc/np - updated : 03-11-2007
HGNC name serine dehydratase
HGNC id 10691
Location 12q24.13      Physical location : 113.830.251 - 113.841.692
Synonym name
  • L-serine ammonia-lyase
  • L-serine deaminase
  • Synonym symbol(s) SDH, SBDS
    EC.number 4.3.1.17
    DNA
    TYPE functioning gene
    STRUCTURE 11.00 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    regulatory sequence
    MAPPING cloned Y linked N status provisional
    Map cen - D12S78 - D12S317 - D12S353 - D12S330 - D12S1605 - D12S84 - D12S1645 - SDS - D12S1646 - D12S79 - qter
    Authors Gene Map (98)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 1620 34.7 328 - Sun (2003)
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Endocrineadrenal gland    
    Reproductivefemale systemovary   
    Visualeye    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer homomer , dimer
    HOMOLOGY
    interspecies ortholog to murine Sds
    homolog to Drosophila sdhb
    Homologene
    FAMILY serine/threonine dehydratase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • catalyzing the pyridoxal phosphate (PLP) dependent deamination of L-serine to yield pyruvate
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS