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FLASH GENE

Symbol

PRSS21

contributors: SGE - updated : 30-04-2010

HGNC name	protease, serine, 21 (testisin)
HGNC id	9485

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in ovarian cancer tumoral     --low   in testicular tumors (role in progression of testicular tumor of germ cell origin)

Susceptibility

Variant & Polymorphism

Candidate gene	aberrant regulation of PRSS21 may underlie certain secondary male infertility syndrome, such as "easily decapited spermatozoa"
Marker
Therapy target
	System Type Disorder Pubmed cancer     target for therapeutic intervention in cancer

ANIMAL & CELL MODELS