| protein
| interacting with RNF25 |
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interaction between IRAK1BP1 and RELA enhances RELA transactivation activity  |
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interacting with NFKBIB (tight control of NFKBIB protein by RELA is necessary for the maintenance of cellular homeostasis) |
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interacting with PIAS3, to suppress NFKB transcription |
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bound to nucleosomes following deacetylation of H3K9 by SIRT6 (SIRT6-mediated deacetylation of H3K9 promotes RELA destabilization from target gene chromatin and termination of NF-KB |
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association of SIRT6 with RELA target promoters (SIRT6 levels might influence RELA-dependent transcription) |
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associates with alpha-actinin-4 (alpha-actinin-4 is important for the NF-kappaB nuclear translocation and its functions inside the nucleus |
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interacting with PDLIM2 |
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interacting with IER3 (direct interaction with the C-terminal region of the subunit RELA harbouring the transactivation domain of the NF-kappaB transcription factor) |
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interacting with PSMD10 |
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binds COMMD1, the rate-limiting component of the RELA ubiquitin ligase complex, in response to stress |
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direct contact between RELA and Mediator, through the MED17 subunit and the TA1 and TA2 regions of RELA |
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interaction between RELA and STAT5B in chondrocytes |
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reciprocal functional interaction between RELA and IGF1 in which the transcription factor modulates both IGF1 synthesis and action in growth plate chondrocytes |
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ability of RELA to directly recruit DNMT1 to chromatin, resulting in promoter-specific methylation and transcriptional repression of tumor metastasis suppressor gene BRMS1 |
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NFKB is a strong inhibitor of collagen synthesis and of COL1A1 transcription in healthy and scleroderma fibroblasts, and RELA subunit of NFKB being responsible for the inhibitory action |
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ERG controls endothelial cell quiescence by repressing activity of nuclear factor RELA |
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NAA10 inhibits apoptosis through NAA10-RELA-dependent MCL1 transcriptional activation |
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redundant functions of GSK3A and GSK3B through phosphorylation of RELA at Thr-254 play a crucial role in early stages of chondrocyte differentiation |
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PTK2B is a critical regulator of endothelial cell (EC) inflammation by virtue of engaging IKK to promote the release and the transcriptional capacity of RELA, and, additionally, by its ability to facilitate the nuclear translocation of the released RELA |
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KLF11 potently inhibits NFKB signaling pathway via physical interaction with RELA |
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PPARG acts as an E3 ubiquitin ligase, physically interacting with RELA to induce its ubiquitination and degradation |
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in the nucleus, ACTN4 functions as a selective transcriptional co-activator of RELA |
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ING4 acts as an E3 ubiquitin ligase to induce ubiquitination of RELA and degradation, which is critical to terminate NFKB activation |
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inhibition of FGF10 by inflammatory signaling involves the NFKB1-dependent interactions between RELA, SP3, and the FGF10 promoter |
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HES6, physically and functionally interacts with RELA-containing NF-KB1 complexes in cortical progenitor cells |
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PHF20 induces canonical NFKB1 signalling by increasing the DNA-binding activity of NFKB1 subunit RELA |
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RELA p65-dependent transcriptional activation of EIF4H increased the EIF4H protein content augmenting the rate of global protein synthesis |
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nuclear import of RELA mainly relies on the canonical KPNA2/KPNB1 pathway |
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RELA is a potent transcriptional activator of ADAMTS5 in chondrocytes during osteoarthritis development |
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RELA and STAT1 cooperate to control NOS2 gene transcription in response to proinflammatory cytokines by a coactivator exchange mechanism |
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BEX2 promotes proliferation of human glioblastoma cells via NFKB1 signaling pathway and BEX2 nuclear location is critical for RELA expression |
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CDK6 physically and functionally interacts with the NFKB1 subunit RELA in the nucleus and is found at promoters of many transcriptionally active NFKB1 target genes |
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PPIA provided stability for RELA and promoted RELA nuclear translocation, resulting in increased nuclear accumulation and enhanced NFKB1 activity |
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ECSIT specifically interacted with RELA/NFKB1 proteins, which colocalized in the nucleus |
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RMDN3 mRNA and protein expression is regulated by RELA |
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KPNB1 transports nuclear factor RELA from the cytoplasm to the nucleus to increase pro-inflammatory genes expression |
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through its acidic transactivation domain (TAD), RELA has the capacity to form interactions with several different transcriptional regulatory proteins, including GTF2B, GTF2H1, EP300 and TAF9B |
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RNF182 promotes the degradation of RELA via K48-linked ubiquitination, resulting in the inhibition of TLR-triggered innate immune responses |
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TNF regulates the induction of MACC1 via RELA and the transcription factor JUN in Colorectal cancer cells |
