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FLASH GENE

Symbol

VAX2

contributors: mlc/np - updated : 03-11-2007

HGNC name	ventral anterior homeobox 2
HGNC id	12661

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

helix turn helix, DNA binding domain

HOMOLOGY

Homologene

FAMILY

EMX homeobox family

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION	playing a crucial role in eye development and, in particular, in the specification of the ventral optic
	vesicle
	controlling the patterning of the eye dorsoventral axis
	may be a regulator of axial polarization in the retina

CELLULAR PROCESS

nucleotide, transcription

PHYSIOLOGICAL PROCESS

development

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS