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FLASH GENE
Symbol VAX2 contributors: mlc/np - updated : 03-11-2007
HGNC name ventral anterior homeobox 2
HGNC id 12661
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 1164 31 290 - Barbieri (1999)
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo, pregnancy
Text specifically, in the developing vertebral eye (in the ventral part of the optic vesicles)
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • helix turn helix, DNA binding domain
    • HOMOLOGY
    Homologene
    FAMILY EMX homeobox family
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • playing a crucial role in eye development and, in particular, in the specification of the ventral optic
    • vesicle
  • controlling the patterning of the eye dorsoventral axis
  • may be a regulator of axial polarization in the retina
    • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS