Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

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FLASH GENE

Symbol

IKBKG

contributors: mct/npt/pgu - updated : 14-03-2018

HGNC name	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
HGNC id	5961

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

IP2 , OLEDAID , EDAID , IMD33

related resource

IKBKGbase: Mutation registry for Nemo deficiency

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional       loss of function in the adult epidermis, causing an inflammatory skin phenotype

Susceptibility

to mycobacteria to Behçet disease

Variant & Polymorphism other	mutations impairing CD40-dependent IL-12 production linked to susceptibility to mycobacteria
	heterozygous mutation is a cause of familial occurrence of Behçet disease in female patients

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer digestive liver IKK-targeted gene therapy can be used in the treatment of hepatocellular carcinoma, a cancer that is notoriously resistant to radiation and chemotherapy

ANIMAL & CELL MODELS