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FLASH GENE

Symbol

SCN9A

contributors: mct/npt - updated : 27-10-2017

HGNC name	sodium channel, voltage-gated, type IX, alpha subunit
HGNC id	10597

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

ETHA , CIEP , PEXPD , GEFSP2

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in prostate cancer (Diss 2008) constitutional germinal mutation     loss of function loss-of-function mutations in a single gene, SCN9A, cause a general loss of two major senses—nociception and smell

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target	extremely promising target for selective pharmaceutical intervention in the analgesia

ANIMAL & CELL MODELS