Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol CD79B contributors: np/ - updated : 22-07-2006
HGNC name CD79b molecule, immunoglobulin-associated beta
HGNC id 1699
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunelymph node   highly
 spleen   highly
 tonsils   highly
Reproductivemale systemprostate  moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/ImmuneB cell
cell lineage
cell lines
fluid/secretion lymph
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an immunoglobulin-like V-type domain (ITAM)
    • conjugated GlycoP , PhosphoP
    HOMOLOGY
    interspecies ortholog to murine Igb
    homolog to rattus Igb
    homolog to C.elegans Y119C1B.B
    Homologene
    FAMILY
  • immunoglobulin superfamily
    • CATEGORY antigen , receptor membrane
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type I membrane protein
    basic FUNCTION
  • encodes the Ig-beta protein of the B-cell antigen component
  • associated to surface IgM-receptor, may be involved in signal transduction
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling signal transduction
    a component
  • B-cell antigen component
  • heterodimer of alpha and beta chains, disulfide-linked
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other phosphorylated on tyrosine as a result of B cell activation
    ASSOCIATED DISORDERS
    corresponding disease(s) AGM6
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS