basic FUNCTION
| displaying chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages |
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might play a pivotal role in the pathobiology of pancreatic cancer, probably by regulating cancer invasion |
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fights bacteria at the earliest stage of infection, well before the establishment of inflammation, and thus fulfills a unique role in antimicrobial immunity |
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autocrine stimulator of fibroblast growth and migration, with multi-modal tumor-stimulatory activities |
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involved in the homeostasis of monocyte-derived macrophages rather than in inflammation |
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having suppressive activity toward tumor progression of oral carcinoma |
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possesses chemoattractive activity for activated macrophages, immature dendritic cells and natural killer cells |
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having ability to stimulate granule cell migration, suggesting that it must be involved in the postnatal maturation of the cerebellum |
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negative regulator of growth and metastasis in breast cancer |
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monocyte-selective chemokine expressed in all normal tissues, but is also involved in the development of several cancers |