| basic FUNCTION
| catalyzing the first and rate-limiting step in the coonversion of cholesterol to bile acids |
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playing a role in the alternative bile acid synthesis pathway |
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hydroxylates carbons 6 and 7 of the B ring of oxysterols and steroids (Stiles 2009) |
|
balancing prostate hormone levels in human cells |
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importance of CYP7B1 in bile salt synthesis and the role of the enzyme in the inactivation of otherwise hepatotoxic oxysterols (Stiles 2009) |
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CYP7B1-mediated catalysis may play a role for control of the cellular levels of androgens, not only of estrogens (Pettersson 2009) |
