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FLASH GENE

Symbol

SLC17A4

contributors: npt/ - updated : 24-10-2007

HGNC name	solute carrier family 17 (sodium phosphate), member 4
HGNC id	10932

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	6p22-p21.3      Physical location : 25.754.926 - 25.781.402
Synonym name	solute carrier family 17 member 4
	Na/PO4 cotransporter
	putative small intestine sodium-dependent phosphate transport protein
Synonym symbol(s)	KIAA2138, KAIA2138, MGC129623

DNA

TYPE	functioning gene
STRUCTURE	25.47 kb     12 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed SLC17A4 12 - 2626 54 497 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine small intestine         intestine large intestine colon       liver         Endocrine pancreas

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial secretory glandular endocrine   Epithelial secretory glandular exocrine

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	twelve putative transmembrane segments
	cytosolic N and C termini
	a motif in the fourth TM domain charcacteristic of the ACS family

HOMOLOGY

interspecies	homolog to Drosophila CG8791
	homolog to C.elegans F21F8.11

Homologene

FAMILY	major facilitator superfamily
	sodium/anion cotransporter family

CATEGORY

transport carrier

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

involved in actively transporting phosphate into cells via Na+ co-transport

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

active transport

text	sodium phosphate cotransporter (symporter)

PATHWAY

metabolism

other

signaling

phosphate metabolism

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS