| basic FUNCTION
| may be involved in cell-cell interactions and recognition |
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receptor tyrosine kinase that acts as a collagen IV adhesion receptor |
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plays an important role as a collagen receptor, mediating intimal thickening after vascular injury  |
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a key mediator of the stromal-epithelial interaction during ductal morphogenesis in the mammary gland |
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central mediator of smooth muscle cell migration |
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required for cell-mediated calcification of the matrix |
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mediates an important mechanism for atherosclerotic calcification |
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regulates the stabilization of cell surface E-cadherin and E-cadherin-mediated cell aggregation |
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its expression increases epithelial plasticity |
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promotes cell-cell adhesion and differentiation through stabilization of E-cadherin, which is mediated by CDC42 inactivation |
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promotes E-cadherin-mediated adhesion |
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exerts prosurvival effect, at least in part, through the functional interaction with NOTCH1 |
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acts as a novel upstream regulator for Notch1 signaling, that Notch1 functions as an important effector for DDR1-mediated survival in both the TP53-dependent and p53-independent responses to genotoxic stress |
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nonintegrin tyrosine kinase receptor for collagen implicated in cell adhesion, proliferation, and extracellular matrix remodeling |
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plays an important role in the pathogenesis of renal disease via enhanced inflammation |
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DDR1 and DDR2 are receptor tyrosine kinases that signal in response to collagen |
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while DDR1b clusters co-localized with non-fibrillar collagen, DDR1b/DDR2 filamentous structures associated with collagen fibrils |
