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FLASH GENE

Symbol

MTX2

contributors: mlc - updated : 26-10-2007

HGNC name	metaxin 2
HGNC id	7506

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - - 1385 - 263 - Xie (2007) variant 2 - - 1589 - 253 - Xie (2007)

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Hearing/Equilibrium ear       highly Reproductive male system testis     highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal   highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a glutathione S-transferase consensus sequence
	lacking the C terminal outer membrane signal-anchor domain present in MTX1

HOMOLOGY

interspecies

homolog to C.elegans Cel ZC97.1

Homologene

FAMILY

CATEGORY

transport carrier

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,mitochondria,outer

basic FUNCTION

putatively involved in protein import into mitochondria

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein	metaxin binding
	association with six other proteins, metaxins 1, CHCHD3, CHCHD6 and DNAJC11, SAMM50, IMMT (putative role in protein import related to maintenance of mitochondrial structure)

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS