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FLASH GENE
Symbol CCKBR contributors: mct/npt - updated : 20/09/2008
HGNC name cholecystokinin B receptor
HGNC id 1571
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven transmembrane segments (7TM) receptor
  • an ITIM-like motif required for interaction with PTPN11 and the activation of the AKT pathway
    • HOMOLOGY
    Homologene
    FAMILY
  • G protein coupled receptor superfamily
    • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • stimulating the phosphatidylinositol cycle and intracellular Ca2+ mobilization
  • may have a role in the regulation of the circadian rhythm, the metabolism of cerebral cholesterol and in the regulation of the plasminogen system (Hansen 2008)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS behavioral
    text modulator of anxiety, pain, inhibitor of dopamine mediator behaviors
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS