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FLASH GENE
Symbol MYO9A contributors: mlc/np - updated : 05-11-2007
HGNC name myosin IXA
HGNC id 7608
Location 15q22-q23      Physical location : 72.118.368 - 72.410.422
Synonym symbol(s) FLJ11061, FLJ13244, MGC71859
DNA
TYPE functioning gene
STRUCTURE 291.00 kb     42 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Physical map
UACA 15q22-q24 uveal autoantigen with coiled-coil domains and ankyrin repeats LOC123397 15q22.32 similar to 60S ribosomal protein L29 (Cell surface heparin binding protein HIP) FLJ11196 15q22.32 acheron LOC390601 15 similar to keratin 8, type II cytoskeletal - human THAP10 15q22.32 THAP domain containing 10 FLJ20156 15q22.32 hypothetical protein FLJ20156 LOC283675 15q22.32 similar to ribosomal protein L5; 60S ribosomal protein L5 LOC196993 15q22.32 hypothetical protein LOC196993 LOC390602 15 similar to High mobility group protein 1 (HMG-1) (Amphoterin) (Heparin-binding protein p30) LOC196994 15q22.32 similar to hypothetical protein LOC388132 15 similar to 60S ribosomal protein L17 (L23) FLJ13710 15q22.33 hypothetical protein FLJ13710 NR2E3 15q24 nuclear receptor subfamily 2, group E, member 3 MYO9A 15q22-q23 myosin IXA PRSC2 15q22.32 protease, cysteine, 2 (NEDD8 specific) LOC196996 15q22.33 hypothetical protein LOC196996 PKM2 15q24-q25 pyruvate kinase, muscle LOC56965 15q22.33 hypothetical protein from EUROIMAGE 1977056 BRUNOL6 15q24 bruno-like 6, RNA binding protein (Drosophila) HEXA 15q23-q24 hexosaminidase A (alpha polypeptide) FLJ13315 15q22.33 hypothetical protein FLJ13315 LOC388133 15 hypothetical gene supported by AK026491; NM_000976 LOC338949 15q22.33 similar to RIKEN cDNA 4930425N13 LOC390603 15 similar to prohibitin ARIH1 15q24 ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) GOLGA6 15q22.33 golgi autoantigen, golgin subfamily a, member 6 LOC123346 15q22.33 hypothetical protein LOC123346 BBS4 15q22.3-q23 Bardet-Biedl syndrome 4 DKFZP434B195 15q22.33 hypothetical protein DKFZp434B195 NEO1 15q22.3-q23 neogenin homolog 1 (chicken) LOC388134 15 LOC388134 HCN4 15q24-q25 hyperpolarization activated cyclic nucleotide-gated potassium channel 4
regionally located located in the BBS4 region
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
42 - 8704 292.7 2548 - Hiller (2005)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunelymph node   highly
Reproductivefemale systemuteruscervix highly
 female systemplacenta  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal motor domain
  • ATP and actin-binding sites
  • a neck with two insertions, conforming to the IQ motif calmodulin or calmodulin-like light chain binding domains
  • a tail region with a GAP (GTPase-activating protein) domain
  • HOMOLOGY
    Homologene
    FAMILY
  • myosin family
  • CATEGORY motor/contractile
    SUBCELLULAR LOCALIZATION     intracellular
    basic FUNCTION
  • unconventional myosin, of unknown function
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS