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FLASH GENE
Symbol OTP contributors: npt - updated : 06-11-2007
HGNC name orthopedia homeobox
HGNC id 8518
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbraindiencephalonhypothalamus  
 braindiencephalonamygdala  
Respiratorylung    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a helix-turn-helix DNA binding domain
  • a homeo domain
    • HOMOLOGY
    interspecies homolog to murine Otp
    homolog to Drosophila otp
    intraspecies homolog to orthopedia gene
    Homologene
    FAMILY
  • homeodomain (HD) family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • playing key roles in the specification of cell fates
  • functioning during brain development
    • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS development
    text neurogenesis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS