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FLASH GENE

Symbol

OTP

contributors: npt - updated : 06-11-2007

HGNC name	orthopedia homeobox
HGNC id	8518

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed OTP 3 - 2702 35.1 325 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain diencephalon hypothalamus       brain diencephalon amygdala     Respiratory lung

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a helix-turn-helix DNA binding domain
	a homeo domain

HOMOLOGY

interspecies	homolog to murine Otp
	homolog to Drosophila otp

intraspecies

homolog to orthopedia gene

Homologene

FAMILY

homeodomain (HD) family

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION

basic FUNCTION	playing key roles in the specification of cell fates
	functioning during brain development

CELLULAR PROCESS

nucleotide, transcription

PHYSIOLOGICAL PROCESS

development

text	neurogenesis

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS