basic FUNCTION
| chemotatic activity for monocytes, resting T-lymphocytes and neutrophils |
|
inhibiting proliferation of myeloid progenitor |
|
cells in colony formation assays |
|
chemokine that was initially characterized as a chemoattractant for monocytes and dendritic cells (Han 2009) |
|
may play a direct role in angiogenesis, via the upregulation of MMP2 expression |
|
promoted the chemotactic migration and differentiation of endothelial cells, and endothelial cell migration was mediated through CCR1 (Hwang 2005) |
|
promoted VEGF-induced endothelial proliferation and migration, which were correlated with the maximal stimulation of KDR expression by CCL23 (Han 2009) |
|
results in up-regulation of KDR receptor gene transcription and protein expression and that KDR/Flk-1 up-regulation induced by CCL23 may contribute to potentiation of VEGF action in angiogenesis (Han 2009) |