Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

Home Page

FLASH GENE

Symbol

SULF1

contributors: mct/npt - updated : 31-05-2017

HGNC name	sulfatase 1
HGNC id	20391

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

DEL8Q13

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in the majority of cancer cell lines examined, and forced expression of SULF1 decreases cell proliferation, migration, and invasion (Lai 2008) constitutional     --over   in degenerative intervertebral disc cells

Susceptibility

to recurrent miscarriage

Variant & Polymorphism

Candidate gene
Marker
Therapy target	targeting SULF1 or the interaction between SULF1 and the related sulfatase 2 will potentially be important in developing novel cancer therapies (Lai 2008)

ANIMAL & CELL MODELS