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FLASH GENE
Symbol ACTL7B contributors: mct - updated : 06-04-2021
HGNC name actin-like 7B
HGNC id 162
Location 9q31.3      Physical location : 111.616.870 - 111.618.275
Synonym name
  • testis tissue sperm-binding protein Li 43a
  • Synonym symbol(s) t-actin 1, Tact1
    DNA
    TYPE functioning gene
    SPECIAL FEATURE head to head
    text located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31
    STRUCTURE 1.40 kb     1 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    regionally located located in a "head to head" orientation with ACTL7A from the HSAN3 region
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 1399 - 415 - 2003 12907721
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    Reproductivemale systemtestis    Homo sapiens
     male systemprostate   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • an actin fold (actin-binding left)
  • a single conserved putative protein kinase C site with a single conserved CAMP/c GMP dependent phosphorylation site
  • HOMOLOGY
    interspecies ortholog to murine t-actin1
    Homologene
    FAMILY ARP actin-related proteins superfamily
    CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    intracellular,cytoplasm,cytoskeleton
    intracellular,nucleus
    basic FUNCTION
  • testicular germ cell-specific intronless gene
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    repressed by methylation of CpG dinucleotides in somatic cells
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS