Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | PEMT | contributors: npt/mct/pgu - updated : 23-09-2010 |
HGNC name | phosphatidylethanolamine N-methyltransferase |
HGNC id | 8830 |
|
DNA |
TYPE | like-sequence |
STRUCTURE | 86.12 kb 7 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | status | confirmed |
Map | see SMCR (phenotype) |
regionally located | within the Smith-Magenis critical region |
RNA |
TRANSCRIPTS | type | messenger |
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text | three transcripts of translation iniation site differing from each other in the 5' region with the point of divergence being 15nt upstream the translation initiation site (PMID: 9989271) |
EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
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HOMOLOGY |
Homologene |
FAMILY |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,endoplasmic reticulum | |
intracellular,cytoplasm,organelle,Golgi | |
intracellular,cytoplasm,cytosolic |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
Other | regulated by estrogen in human hepatocytes |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Susceptibility |
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Variant & Polymorphism SNP , other | |
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |