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FLASH GENE
Symbol KCNK7 contributors: - updated : 03-10-2007
HGNC name potassium channel, subfamily K, member 7
HGNC id 6282
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1312 - 307 - Salinas, Goldstein
- splicing 1388 - 252 - Salinas, Goldstein
truncated
- - 1577 - 257 - Salinas, Goldstein
truncated
- - 1485 - 252 - Goldstein
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Nervousbrain   predominantly
Reproductivefemale systemplacenta   
Respiratorylung    
Visualeye    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • four transmembrane domains
  • two pore forming regions with two P domains arranged like a tandem of inward rectifier channels
  • mono polymer homomer , dimer
    HOMOLOGY
    Homologene
    FAMILY potassium channel, subfamily K
    CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION may require other non-pore-forming proteins for activity
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS