basic FUNCTION
| catalyzing the the first step of the proteolytic processing of farnesylated protein converting enzyme 2, including Ras |
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has important functional interaction with the P2' and P3' substrate positions in addition to the farnesylated cysteine at the scissile bond site |
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required for lamin B1 endoproteolysis, and involved in integrity of the nuclear lamina |
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promotes a proteolytic activity that is required for the maturation of RAS, and certain other proteins whose precursors bear a C-terminal CAAX tetrapeptide motif |
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involved in the cleavage of the CAAX motif of RAS, motif that are essential for its proper membrane localization and function |
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cysteine protease, but has also metalloprotease-like activity and loss of RCE1 blocks proper RAS localization and impedes cell growth and transformation |
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essential for the intracellular trafficking of PDE6A,PDE6B, PDE6C, PDE6D and survival of photoreceptor cells |
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required for the proper function of photoreceptor cells |
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not needed for the development of retinal neurons but is specifically required for the maintenance of photoreceptor cells |