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FLASH GENE
Symbol RPH3AL contributors: - updated : 26-10-2005
HGNC name rabphilin 3A-like (without C2 domains)
HGNC id 10296
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • putative zinc finger protein motif
  • a conserved Rab3-binding domain (RBD3)
    • HOMOLOGY
    interspecies homolog to rattus Rph3al
    Homologene
    FAMILY
    CATEGORY regulatory , transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,granule
    intracellular,cytoplasm,cytoskeleton
    text cytoskeletal protein binding protein
    basic FUNCTION
  • involved in regulated endocrine exocytosis
  • involved in the recruitment of secretory granules at the plasma membrane possibly via the interaction with UNC13B
  • functioning as a potential RAB3B effector protein in epithelial cells
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS exocytosis transport
    text vesicular transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein cytoskeletal protein binding protein(cytoskeleton LIM domain-containing protein zyxin)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS