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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

RPH3AL

contributors: - updated : 26-10-2005

HGNC name	rabphilin 3A-like (without C2 domains)
HGNC id	10296

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart         Digestive liver           stomach         Endocrine pancreas           thyroid         Reproductive female system ovary       Urinary kidney

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial secretory glandular endocrine   Epithelial secretory glandular exocrine   Muscular striatum cardiac     Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	putative zinc finger protein motif
	a conserved Rab3-binding domain (RBD3)

HOMOLOGY

interspecies

homolog to rattus Rph3al

Homologene

FAMILY

CATEGORY

regulatory , transport

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytosolic,granule
	intracellular,cytoplasm,cytoskeleton
text	cytoskeletal protein binding protein

basic FUNCTION	involved in regulated endocrine exocytosis
	involved in the recruitment of secretory granules at the plasma membrane possibly via the interaction with UNC13B
	functioning as a potential RAB3B effector protein in epithelial cells

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

exocytosis transport

text	vesicular transport

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cytoskeletal protein binding protein(cytoskeleton LIM domain-containing protein zyxin)

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS