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FLASH GENE
Symbol TRAF3 contributors: mct/pgu - updated : 14-03-2017
HGNC name TNF receptor-associated factor 3
HGNC id 12033
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
higher both in patients with Crohn disease and ulcerative colitis than in healthy controls
constitutional       loss of function
suffices to metabolically reprogram B cells, a finding that improves our understanding of the role of TRAF3 as a tumor suppressor
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS