| basic FUNCTION
| cell surface adhesion receptor mediating cell-adhesion to extra cellular matrix or to other cells, through hetero dimerization and connecting to the cytoskeleton and various signaling molecules within cells |
|
allows retinal pigmented epithelial cells adhesion on Bruch's membrane in wet age-related macular degeneration (Afshari 2010) |
|
can induce and localise to focal adhesions in a high activation state, whereas its intermediate activity state normally supports cell adhesion consistent with migration (Lydolph 2009) |
|
contributing to adhesion and differentiation of hematopoietic stem and progenitor cells in the endosteal stem cell niche (Schreiber 2009) |
|
critical intrinsic regulator that controls the development of autoimmune arthritis (Kanayama 2009) |
|
involved in the attraction of neutrophils via its binding to osteopontin (Nishimichi 2009) |
|
receptor for nerve growth factor, brain-derived neutrophic factor and NT3 (Staniszewska 2008) |
