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FLASH GENE
Symbol AQP8 contributors: mct/npt - updated : 24-11-2007
HGNC name aquaporin 8
HGNC id 642
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • six transmembrane segments (6TM)
  • intracellular N and C termini
  • HOMOLOGY
    Homologene
    FAMILY
  • MIP/aquaporin family
  • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • ‘‘orthodox’’aquaporin, that transport only water molecules (Sorani 2008)
  • forming a water-specific channel, mercury-sensitive
  • not permeable to glycerol or urea
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS