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FLASH GENE

Symbol

DLK1

contributors: mct - updated : 06-01-2016

HGNC name	delta-like 1 homolog (Drosophila)
HGNC id	2907

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	transgenic mice overexpressing soluble DLK1 in adipose tissue or liver show a marked decrease in adiposity, with reduced adipogenesis and adipocyte marker expression
	Dlk1(-/-) mice were developmentally retarded in their muscle mass and function owing to inhibition of the myogenic program during embryogenesis